Survival Analysis
In this panel, you can perform survival analysis based on the expression status of one gene or a multi-genes' signature and plot a Kaplan-Meier curve. Some genesets are provided.
GEPIA performs Overall Survival (OS) or Progression-free Interval (PFI) analysis based on gene expression `log2 (TPM+1)` transformed. GEPIA uses Log-rank test, a.k.a the Mantel-Cox test, for hypothesis test. Cohorts thresholds can be adjusted. The cox proportional hazard ratio and the 95% confidence interval information can also be included in the survival plot.
Parameters:
- Gene: Input a gene/isoform or geneset of interest
- Time Response: Select the OS or PFS survival response.
- Axis Units: Select Month or Day unit for plotting.
- Datasets Selection: Select one or multiple cancer types of interest in the "Dataset" field and click "+" to build dataset list in the "Selected Datasets" field.
- Colors: Choose color to plot
- Group Cutoff: Select a suitable expression threshold for splitting the high-expression and low-expression cohorts.
- Cutoff-High(%): Samples with expression level higher than this threshold are considered as the high-expression cohort.
- Cutoff-Low(%): Cutoff-Low(%): Samples with expression level lower than this threshold are considered the low-expression cohort.
TCGA Abbr.
| Abbr | Detail |
|---|---|
| ACC | Adrenocortical carcinoma |
| BLCA | Bladder Urothelial Carcinoma |
| BRCA | Breast invasive carcinoma |
| CESC | Cervical squamous cell carcinoma and endocervical adenocarcinoma |
| CHOL | Cholangiocarcinoma |
| COAD | Colon adenocarcinoma |
| DLBC | Lymphoid Neoplasm Diffuse Large B-cell Lymphoma |
| ESCA | Esophageal carcinoma |
| GBM | Glioblastoma multiforme |
| HNSC | Head and Neck squamous cell carcinoma |
| KICH | Kidney Chromophobe |
| KIRC | Kidney renal clear cell carcinoma |
| KIRP | Kidney renal papillary cell carcinoma |
| LAML | Acute Myeloid Leukemia |
| LGG | Brain Lower Grade Glioma |
| LIHC | Liver hepatocellular carcinoma |
| LUAD | Lung adenocarcinoma |
| LUSC | Lung squamous cell carcinoma |
| MESO | Mesothelioma |
| OV | Ovarian serous cystadenocarcinoma |
| PAAD | Pancreatic adenocarcinoma |
| PCPG | Pheochromocytoma and Paraganglioma |
| PRAD | Prostate adenocarcinoma |
| READ | Rectum adenocarcinoma |
| SARC | Sarcoma |
| SKCM | Skin Cutaneous Melanoma |
| STAD | Stomach adenocarcinoma |
| TGCT | Testicular Germ Cell Tumors |
| THCA | Thyroid carcinoma |
| THYM | Thymoma |
| UCEC | Uterine Corpus Endometrial Carcinoma |
| UCS | Uterine Carcinosarcoma |
| UVM | Uveal Melanoma |
License Statement: All content on this website is freely available to all users, including for commercial use.